As reported to the FAA. Reports are unverified, and codes are left as the FAA publishes them.
What was found
(CAN) ON TAKEOFF, THE NR 1 MAIN WHEEL DEPARTED THE AIRCRAFT. THE CREW WERE NOT AWARE OF THE CONDITION AND CONTINUED TO DESTINATION WHERE THEY NOTICED THE WHEEL MISSING. GROUND PERSONNEL FOUND THE WHEEL AT THE DEPARTURE AIRPORT NEAR WHERE THE AIRCRAFT ROTATED ON TAKEOFF.