29. ANTICONVULSANTS
BARBITURATE GROUP mephobarbital (Mebaral) metharbital (Gemonil) phenobarbital (Luminal) N-phenylbarbital (Pyrictal) primidone (Mysoline) Undesirable effects in aviation: Excessive sedation and impairment of mental and physical activity.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use; however, Federal Aviation Regulation prohibits duty in persons with convulsive disorders.
HYDANTOINS diphenylhydantoin (Dilantin; Diphentoin; Diphenylan) ethotoin (Peganone) N-methy phenylethyhydantoin (Mesantoin) Undesirable effects in aviation; Minor sedation, hyperplasia of gums, nystagmus, tremor.
Use in aviation personnel: Airman duties contraindicated for 2A hours after use; however, Federal Aviation Regulation prohibits duty in persons with convulsive disorders.
OXAZOLIDONES paramethadione (Paradione) trimethadione (Tridione) Undesirable effects in avlation: Glare phenomenon, rashes, fever.
Use in aviation personnel: Airman duties contraindicated for 3 days after use; however, Federal Aviation Regulation prohibits duty in persons with convulsive disorders.
OTHER ANTICONVULSANTS aminoglutethimide (Elipten) ethosuximide (Zarontin) methsuximide (Celontin) phenacemide (Phenurone) phensuximide (Milontin) 68
Undesirable effects in aviation: Sedation, headache, nausea, vertigo, rash; prolonged use has caused fever and psychosis.
Use in aviation personnel: Airman duties contraindicated for 24 hours after a single dose; for 1 week after more continued use.
ANTIHISTAMINE SEDATIVES promethazine (Phenergan) propiomazine (Largon) Undesirable effects in aviation: Same as short acting barbiturates.
Use in aviation personnel: Airman duties contraindicated for 24 hours after a single dose, or 48 hours after chronic use.
28. SEDATIVES AND HYPNOTICS
HALOGENATED HYDROCARBONS chloral hydrate petrichloral (Perichlor) toloxychlorinol Undesirable effects in aviation: Rapid sedation, but rather short lived. Overdosage may give cardiac depression.
Use in aviation personnel: Airman duties contraindicated for 12 hours after use.
BROMIDES bromides potassium bromide sodium bromide Undesirable effects in aviation: Continued use may cause psychosis and dermatitis.
Use in avlation personnel: Airman duties not contraindicated after a single dose, but prohibited for & weaks after steady use for a week or more; obsolete drugs.
PARALDEHYDE paraldehyde Undesirable effects in aviation; Relatively safe in usual doses, but breath highly offensive for 24 hours or more.
Use in aviation personnel: Airman duties contraindicated for 2 days after use.
UREIDES, CARBAMATES, HIGHER ALCOHOLS allylisopropylacetylcarbamide (Sedormid) bromisovalum (Bromural; Isoval; Kartryl) carbromal (Adalin) ectylurea (Nostyn) emylcamate (Nuncital) ethchlorvynol (Placidyl) ethinamate (Valmid) methylparafynol (Dormison) 65
Undesirable effects in aviation: Relatively feeble depressants and little chance of serious side effects (except for thrombocytopenia from allylisopropylacetylcarbamide).
Use in aviation personnel: Airman duties contraindicated for 24 hours after use.
BARBITURATES, SHORT AND INTERMEDIATE ACTING allylbarbituric acid (Sandoptal) amobarbital (Amytal) aprobarbital (Alurate) butabarbital (Butisol) butallylonal (Pernoston) cyclobarbital (Phanodorn) diallylbarbituric acid (Dial) heptabarbital (Medomin) pentabarbital (Isobarb; Napental; Nembutal; Pembule; Pental) probarbital (Ipral) secobarbital (Barbosec; Evronal; Seconal; Synate) talbutal (Lotusate) vinbarbital (Delvinal) Undesirable effects in aviation: Often initial excitement, then sleepiness, sedation, impairment of mental and physical activity; minor sedation during recovery often not appreciated adequately by patient.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use in usual dosage.
BARBITURATES, LONG ACTING barbital (Veronal) phenobarbital (Luminal) Undesirable effects in aviation: Sedation, prolonged, and impairment of mental and physical activity.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use; however, after a month or more of therapy with usual dosage, certain types of ground work might be permitted for patients in whom the only observable effect was calmness. However, more often the underlying medical condition would preclude duty.
GLUTETHIMIDE GROUP glutethimide (Doriden) methyprylon (Nodular) 66
Undesirable effects in aviation: Variously: drowsiness, ataxia, rashes, diarrhea, leucopenia, hepatic damage.
Use in aviation personnel: Airman duties contraindicated for 3 days after use, or in presence of side effects; however, Federal Aviation Regulation prohibits duty in persons with convulsive disorders.
.....
30. TRANQUILIZERS
PHENOTHIAZINE GROUP acetophenazine (Tindal) chlorpromazine (Thorazine) chlorprothixine (Taractan) fluphenazine (Prolixin) mepazine (Pacatal) methoxypromazine (Tentone) perphenazine (Trilafon) piperacetazine (Quide) prochlorperazine (Compazine) promazine (Sparine) thiopropazate (Dartal) thioridazine (Mellaril) trifluoperazine (Stelazine) triflupromazine (Vesprin) Undesirable effects in aviation: Autonomic and metabolic: weakness, chilliness, constipation, stuffy nose, blurred vision, dry mouth, hypotension. CNS: drowsiness, parkinsonism, akathisia, dystonia. Organ damage: obstructive hepatitis, marrow depression and agranulocytosis.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use of the drug per se; however, patients requiring tranquilizers are ordinarily excluded from duty.
ANTIEMETICS pipamazine (Mornidine) thiethylperazine (Torecan) thioperazine (Vontil) trimethobenzamide (Tigan) Undesirable effects in aviation: Similar to phenothiazine group.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use.
ANTIPRURITICS methdilazine (Tacary!)
trimeprazine (Temaril) 70
Undesirable effects in aviation: Similar to phenothiazine group.
Use in aviation personnel: Work contraindicated for 24 hours after use.
RESERPINE GROUP alseroxylon (Rauwiloid) deserpidine (Harmonyl) rauwolfia (Abten; Koglucoid; Raudixin; Raulon; Rau-Tab;
Rautensin ; Vio-Serpine) rescinamine (Moderil) reserpine (Crystoserpine; Eskaserp; Rau-sed; Reserpoid; Roxinoid; Sandril; Serfin; Serpasil Serpiloid; Serpine) tetrabenazine (Nitoman) Undesirable effects in aviation: Autonomic: nasal congestion, salivation, flushing, vomiting, diarrhea, bradycardia. CNS:
sedation, nightmares, parkinsonism. Other: induction of bleeding in peptic ulcer.
Use in aviation personnel: Airman duties contraindicated for 1 week after use; however, patients requiring tranquilizers are ordinarily excluded from duty.
DIPHENYLMETHANE GROUP azacyclonal (Frenquel) benactyzine (Suavitil) captodiamine (Suvren) haloperidol hydroxyzine (Atarax; Vistaril) piperilate (Sycotrol) Undesirable effects in Aviation: Sedation, autonomic side effects.
Use in aviation personnel: Airman duties contraindicated for 12 hours after use; however, patients requiring tranquilizers are ordinarily excluded from duty.
PROPANEDIOL-CARBAMATE GROUP meprobamate (Equanil; Meprospan; Miltown) oxanamide (Quinctin) phenaglycodol (Ultran) valnoctamide (Axiquel) Undesirable effects in aviation: Tremulousness, muscular relaxation, sleepiness, nausea, depression, allergic reactions, leucopenin, thromocytopenia, intolerance to alcohol, withdrawal symptoms.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use; however, patients requiring tranquilizers are ordinarily excluded from duty.
CHLORDIAZEPOXIDE chlordiazepoxide (Librium) Undesirable effects in aviation: Drowsiness, vertigo, ataxia (in doses over 50 mg. per day), syncope, itching, dermatitis, impaired thinking, confusion.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use; however, patients requiring tranquilizers are ordinarily excluded from duty.
OTHERS amphenidone (Dornwall) clemizole (Allercur) mephenoxalone (Trepidone) Undesirable effects in aviation: Variously: sedation, muscular relaxation.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use; however, patients requiring tranquilizers are ordinarily excluded from duty.
Undesirable effects in aviation: Excitement, nervousness, dry mouth, constipation, impotence, visual disturbances, hypotension, rash, jaundice.
Use in aviation personnel: Airman duties contraindicated for 1 week after use. Medicinal need would probably indicate unfitness for duty.
DIBENZAZEPINE GROUP amitriptyline (Elavil) imipramine (Tofranil) Undesirable effects in aviation: Excitement or drowsiness, dry mouth, blurred vision, tachycardia, constipation, allergic reactions, hypotension, cholestatic jaundice, agranulocytosis, parkinsonism, tremor.
Use in aviation personnel: Work contraindicated for 1 week after use. Medicinal need would probably indicate unfitness for duty.
33. AGENTS IN ALCOHOLISM
METABOLIC INHIBITORS calcium carbide disulfiram (Antabuse) Undesirable effects in aviation: Distressing effects after the ingestion of alcohol: nausea, vomiting, drowsiness, collapse, psychosis.
Use in aviation personnel: Airman duties contraindicated for 2 weeks after use; however, alcoholism precludes duty.
78 10 sulfate) _ 37 Antergan.
Auricidine (gold sodium thio- 14 Antepar (piperazine).
Aureomycin (chlortetracycline) _ 37 Antazoline_ 38 Aturbane (phenglutaramide).. 37 Antamine (pyrilamine maleate)..
53 Atropine_ 76 Antabuse (disulfiram) - 61 Atophan (cinchophen). 24 Ansolysen (pentolinium)..
71 Atarax (hydroxyzine) _ 29 Aniaindone_ Atabrine (quinacrine) - 63 Anileridine_ 28 Astrafer (dextriferon) - 26 nitrate)_.
31 'amino acetate) .. Angitet (pentaerythritol tetra- Aspogen (dihydroxyaluminum 60 Anelix (acetaminophen) _ 60 Aspirin.. 55 Anectine (succinylcholine).
13 Aspidium... 42 Androlone (stanolone)_.
47 magnesium salts.. 42 Androlin (testosterone).
Aspartic acid, potassium and 42 diol)...
20 45 Aadrin (isoproterenol)_. 62) Arthrica (ch Androdiol (methylandrostene- Ancillin (diphenicillin) - 60 Arthropan (choline salicylate) _ Analexin (phenyramidol) 54 Artane (trihexlphenidyl).- 37 Anahiat (thonzylamine) ..
10 Arsphenamine_. 66 Amytal (amobarbital)_.
73 Aromatic spirits of ammonia_. 58 Amylsine (naepaine)..
32 Aromatio fluid extract of cascara. 26 Amyl nitrite..
50 Arlidin (nylidrin) .. Amydricsine_.
39 Aristocort (triamcinolone) - 47 Amurex (methionine) -.
18 Argyrol (silver protein) .. 53 Amprotropine_ 18 Argyn (silver protein). 2 Ampicillin_.
17 Argivene (arginine) _ 31 Arginine glutamate- Amphotericin B..
47 gel)_.
47 Arginine-- Amphogel (aluminum hydroxide 24 Arfonad (trimethaphan). 48, 49, 74 Amphetamine..
49 72 Aramine (meteraminol)_. Amphenidone_.
48, 49 | Aralen (chloroquine) _ mine)_..
41 Aquagen (estradiol). Amphedroxyn (methampheta- 2 G)_. Amphedrine (amphetamine) - 48, 49, 74- 26 Aquacillin (procaine penicillin Amotripbene_.
66 53 Aprobarbital_ Amolanone_.
24 8 Apresoline (hydralazine). Amodiaquin.
31, 62 66 Apomorphine ... Amobarbital.
42 APL (chorionic gonadotropin). 21, 64 Ammonium chloride..
32 cellulose)_. 73 Ammonium carbonate.
Apergel (sodium carboxymethyl Ammoniated mercury_.
60 Apamide (acetaminophen). 41 stance)_- 23, 60 Anturane (sulfpyrazone) - Ammestrogen (estrogenic sub- 42 tropin).. 75 Amitriptyline_.
Antuitrin (chorionie gonado- 48, 49, 74 Amitrene (amphetamine).
12 Antrycide_ 5 Amithiozone_.
53 Antrenyl (oxyphenonium) - 22 Amisometradine..
36 Antivenin_ 47 Amiprote (protein hydrolysate)..
37 Antistine (antazoline). 73 Amiphenazole_ 60 Antipyrine_ 47 sate) -- 12 Antimony potassium tartrate. Aminovitox (protein hydroly- 37 Antihist (pyrilamine maleate). 12 Aminostilbamidine.
Antigens, see Skin test antigens. 47 Aminosol (protein hydrolysate)..
14 Anthelcole (piperazine). 60 Aminopyrine_.
Page Page
77 15 81 Aminopterin.. ino scetate)..
21, 26 Aminophylline. Alglyn (dihydroxyaluminum am- 58 Aminopentamide. 39 Alforone (fludrocortisone)_.
47 Aminonat (proteln hydrolysate) _ 20, 50 Aleudrin (isoproterenol)..
22 Aminometradine. 42 Aldroyd (oxymetholone) _ 68 Aminoglutethimide_ 25 Aldomet (methyldopa)..
21 Aminocardol (eminophylline) . Aldinamide (pyrasinamide) _ 47 Amigen (protein hydrolysate)_. 22 Aldactone (spironolactone) ..
60 Amid-Sal (salicylamide)_. 14 Alcopar (bephenium) ..
63 Amidone (methadone) - 31 Alcid (aluminum hydroxide gel)...
Amethopterin, see Methotrexate. 44. Albumin, normal human serum..
53 Amethone (amolanone). 32 Albolene (liquid petrolatum)-.
60 Amdil (acetaminophen) _ Albamycin (novobiocin)..
49, 74 54 Akineton (biperldin)..
48, Am-Dex (dextroamphetamine) -- 32 Agarol (liquid petrolatum emulafon) 53 Ambutonium. 6 Aerosporin (polymyxin B)...
52, 55 Ambenonium - 49, 74 47 Am-B (protein hydrolyaate) 48, Adrizine (dextroamphetamine) ..
58 Alypin (amydricaine) 49 Adrenalin (epinephrine)..
fone) _ 53 Adiphenine-.
Alvosulfon (diaminodiphenyleul- 36 Adenovirus vaccine..
66 Alurate (aprobarbital) 22 Ademol (flumethiazide) _ 31 Aluminum phosphate. 65 Adalin (carbromal) _.
31 Aluminum hydroxide gel. 20 Acylanid (acetyldigitoxin)..
50 Aludrin (isoproterenol). 16! cin) _--- 47 Altara (methionine) -. Actinomycin D (meractinomy- Altafur (furaltadone). 37 Actidil (triprolidine)..
71 Alseroxylon_. 40 Acthotrop (corticotropin)..
46 Alpha tocopherol. 40 Acthar (corticotropin) _.
28 Alpha-Redical (hydroxocobalamin) 40 ACTH (corticotropin).
63 Alphaprodine. Actase (fbrinolyain) ..
31 gel) __. 17 Acriflavin_.
Alokreen (aluminum hydroxide Achromycin (tetracycline)..
32 "Aloe_ Acetylsulfsoxazole_.
31 amino acetate) _- 60 Acetylealicylic aold.
Alminate (dihydroxyaluminum 11 AcetyIpencillamine.
32 cellulose).-- 20: Acetyldigitoxin_.
Almelose (sodium carboxmethyl 35 Acetotrizoate_..
65 Allylisopropylacetylcarbamide. _ 60 Acetophetidin..
41 Allylestrenol__.. 70 Acetophenazine.
66 Allybarbituric acid. - 22 Acetazolamide.
37 Allergenio preparations- 60 Acetanilid. _ Allecur (clemizole)... 60 Acetaminophen_ 24 Alkavervir_.. 29 Acenocoumarin..
31 ino acetate)... 71 Abten (rauwolfa) ..
Alkam (dihydroxyaluminum am- Page Page INDEX