27. ANTITUSSIVES
EXPECTORANTS ammonium chloride glyceryl guaiacolate (Guaianesin) ipecac sodium iodide Undesirable effects in aviation: Serious side effects unlikely.
Use in aviation personnel: Airman duties not contraindicated by use.
NONNARCOTIC SUPPRESSIVES benzonatate (Tessalon) carbetapentane (Toclase) chlorphendianol (Detigon) dimethoxanate (Clothera) homary lamine noscapine (Nectadon) Undesirable effects in aviation: Occasional mild nausea, dizziness, drowsiness.
Use in aviation personnel: Airman duties not contraindicated by usual dose.
31. STIMULANTS
NIKETHAMIDE GROUP ethamivan (Emivan) nikethamide (Coramine; Nikorin) Undesirable effects in aviation: Toxicity minor; extra-therapeutic doses convulsive.
Use in aviation personnel: Airman duties contraindicated by the use of the drug per se for 48 hours. Medical indication would usually preclude duty for a longer period.
OTHER MEDULLARY STIMULANTS amiphenazole (Daptazole) bemegride (Megimide) pentylenetetrazol (Cardiazol; Metrazol; Pentrazol; Pentrolone) pierotoxin Undesirable effects in aviation: Strong respiratory stimulation, convulsions.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use. However, medical status would presumably preclude duty.
REFLEX STIMULANTS ammonium carbonate aromatic spirit of ammonia Undesirable effects in aviation: Effects minor.
Use in aviation personnel: Airman duties not contraindicated by use per se, but medical need would probably indicate unfitness for duty.
32. PSYCHIC STIMULANTS
XANTHINE GROUP caffeine coffee; tea, and other beverages containing xanthines Undesirable effects in aviation: Wakefulness, tremor, indigestion, nervousness.
Use in aviation personnel: Airman duties not contraindicated by beverage use, but medicinal use would probably indicate unfitness for duty.
SYMPATHOMIMETIC GROUP amphetamine (Amitrene; Amphedrine; Benzedrine) dextroamphetamine (Adrizine; Am-Dex; Dadex; Dexedrine) methamphetamine (Desoxyn) Undesirable effects in aviation: Wakefulness, nervousness, impaired judgment.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use.
DIPHENYLMETHANE GROUP deanol (Deaner) methylphenidate (Ritalin) pipradol (Meratran) Undesirable effects in aviation: Irritability, hyperexcitability, insomnia.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use. Medicinal need would probably indicate unfitness for duty.
AMINE OXIDASE INHIBITORS etryptamine (Monase) iproniazid (Marsilid) isocarboxazid (Marplan) nialamide (Niamid) phenelzine (Nardil) pheniprazine (Catron) (withdrawn) tranylcypromine (Parnate) 74
Page Page Vanquin (pyrvinium) 13 Vonedrine (phenyipropylmethyl- Vaponephrin (racephedrine) - 49 amine) - 49 Varidase (streptokinase-strepto- Vontil (thioperazine) 70 dornase) _ 29 Vasimid (tolazoline) - 51 W Vasodilan (isoxuprine) - 50 Warfarin 29 Vasodilatol (pentaerythritol tet- Wheat germ_ 46 ranitrate) - 26 Whole blood 42 Vasodrine (epinephrine) - 49 Winatrol (stanozolol) - 42 Vasopressin 27 Wyacort (methylprednisolone) 39 49 Wyamine (mephentermine). 49 V-Cillin (phenoxymethylpenicillin) - 2 Velban (vinblastine) - 16 Xanthines.
74 Veralba (protoveratrines A & B). Veriloid (alkavervir) 24 Xeroform (bismuth, tribromphe nate 17 Veronal (barbital) - 66 Aylocaine (lidocaine) - 58 Vesprin (triflupromazine) - 70 | Xylometazoline- 49 Versenate, see Edathamil calcium-disodium. Y Viadril (hydroxydione) - 57 Yatren (chiniofon).
Vinactane (viomycin) - 4 Yellow fever vaccine_ 36 Vinbarbital 66 Yellow mercuric oxide 18 Vinblastine 16 Yodoxin (diiodohydroxyquin) - 9 Vinethane (vinyl ether) - 57 Vinyl ether -57 Vioform (iodochlorhydroxyquin) - Zactane (ethoheptazine). 63 Viomycin Zanchol (florantyrone) - 32 Vio-Serpine (rauwolfia) 71 Zarontin (ethosuximide) - 68 Vistaril (hydroxyzine) - 71 Zephiran (benzalkonium)- 18 Vitamin A. 45 Zinc oxide.. 18 Vitamin B, (cyanocobalamin) - 28 Zine sulfate_ 31 Vitamin K, oxide. 30 Zoxazolamine 23, 56 97 * U. S. COVERNMENT PRINTING OFFICE : 1966 O - 274-949
90 26 trate)_. 26 Oxytriphylline_ Pencard (pentaerythritol tetrani- 27 : Oxytocin__ 2 Penbritin (ampicillin).. Oxytetracycline_ 24 Pempidine... 53 Oxyphenonium_.
66 Pembule (pentabarbital). 53 Oxyphencyclimine_.
13 Pelletierine. 60 Oxyphenbutazone- 68 Peganone (ethotoin)- 62 Oxymorphone__..
33 Pectin_- 42 Oxymetholone- 26 Paveril (dioxyline)_. 39 Oxylone (fluoxolonate).
53 Pavatrine_. 57 Oxygen. -.
53 Pathilon (tridihexethyl) _ 32 Oxycholin (dehydrocholic acid).
5 Pasara (para-aminosalicy lic acid). 14 Oxucide (piperazine)..
54 Parsidol (ethopropazide). 19 OxBoralen (methoxsalen) - 4 Paromomycin.. 10 Oxophenarsine_.
74 Parnate (tranylcypromine). 32 Ox bile extract..
29 Parenzyme (trypsin). 71 Ozanamide_ 33, 62 Paregorio_.. Oxamycin (cycloserine) - 49 mine)_. 2 Oxacillin__ (hydroxyampheta- Paredrine 41 Ovocyclin (estradiol) _ 43 Parathyroid injection_ 20 Ousbain__ 43 jection)_. 49 Otrivin (xylometazoline) - Parathormone (parathyroid in- 49 Orthoxine (methoxyphenamine).
5 acid)_. 58 Orthoform_.
(para - aminosalicylic Parasal 58 Orthocaine (orthoform).
5 acid)_ 54 Orphenadrine..
Parapas (para - aminosalicylic Orisul (sulfaphenazole).
1 Para-nitrosulfathiazole_. 43 Orinase (tolbutamide) _ 68 Paramethadione_. 42 Orgasteron (normetandrone).
65 Paraldehyde_ 42 Oreton-M (methyltesterone).
56 Paraflex (chlorzoxazone). 42 Oreton-F' (testosterone)_.
68 Paradione (paramethadione). 22 Oretic (hydrochlorothiazide).
39 Paracort (prednisone). 41 Orestralyn (ethinyl estradiol).
5 Para-aminosalicylic acid. 29 Orenzyme (trypsin) ..
27 Papaverine_ 42 Ora-Testryl (fluoxymesterone).
29 Panwarfin (warfarin)_ 55 Oranixon (mephenesin).
45 Pantothenic acid... 41 Ora-Lutin (ethisterone) - 62 Pantopon_ 35 Orabilex (bunamiodyl) - 35 Pantopaque (iophendylate). 33, 62 Opium_.
54 Panparnit (caramiphen). 58 Opthaine.
Panmycin (tetracycline). 45 Oleovitamin A.
29 Pancreatio dornase_ Oleandomycin.
49 mine) _-- 60 Oll of wintergreen- (phenylpropanola- Panamine 18 Oil of eucalyptus_ acid)_. 18 Oil of cloves_.
Pamisy) (para - aminosalicylic 14 Oil of chenopodium_ 53 Pamine (methscoplamine) -. 49 Oenethyl (methylaminoheptane) Pamaquine_ 26 Octyl nitrite_.
8 Paludrine (chlorguanide). 26 | Octrite (octyl nitrite) - 63 Palfum (dextromoramide). 41 Octofollin (benzestrol).
54 Pagitane (cycrimine) -- 49 Octin (isometheptene) - 70 Pacatal (mepazine).. 53 Octatropine..
Page Page Pr
89 Nystatin_ 52, 55 Neostigmine...
50 Nylidrin_. 42 dil) _.
Nydrazid (isoniazid)..
Nuprin (sulfamoxole). 12 58 Nupercaine (dibucaine) _ 4 Neomycin..
65 62 Numorphan (oxymorphone).. Nuncital (emylcamate). 40 32 Nujol (liquid petrolatum).
68 N-phenylbarbital. 35 58 Novocaine (procaine). 21 Novobiocin_. 42 41 Novestrol (ethinyl estradiol). 37 53 Novatrin (homatropine) ... 42 65 Nostyn (ectylurea) - 61 Neocincophen..
64 Noscapine. 58 48, 50 Norodin (methamphetamine). 10 42 Normetandrone_ 37 ate) ..
14 Normal human plasma..
42 Norlutin (norethindrone) .. 66 42 Norethynodrel. 64 42 Norethindrone_ 22 I 42 Norethandrolone. 32 cellulose)_.
49 Nordefrin 66 Nodular (methyprylon) - 74 68 N-methylphenylethylhydantoin. 22 32 emulsion) _ 18 Nivea cream (liquid petrolatum 12 Nitrous oxide_ 49 Naphazoline_.
Nitromersol. 66 i Nitrogen mustard. 42 Nandrolone_.
Nitrofurazone__ 62 Nalorphine_.
Nitrofurantoin_ 62 Nitoman (tetrabenazine) . 58 Naepaine. _ zole) _. 53 Nisulfazole (para-nitrosulfathia- 42 Nisentil (alphaprodine).
Nionate (ferrous gluconate) - N quin) ..
Nioform (iodochlorhydroxy- 55 Mytolon (benzoquinonium).
42 Nilevar (norethandrolone) _ 52, 55 Mytelase (ambenonium) - 73 Nikorin (nikethamide) .. 68 Mysoline (primidone)..
73 Nikethamide__ 26 Myodil (amotriphene) - 45 Nicotinic acid amide_. 10 malate) _ 23, 45 Nicotinic acid... Myochrysine (gold sodium thio- 74 Niamid (nialamide) _. 15 Myleran (bisulfan).
74 Nialamide. 54 Mydriacyl (tropicamide) - amide. Mycostatin (nystatin)..
Niacinamide, see Nicotinic acid 4 Mycifradin (neomycin)..
Niacin, see Nicotinic acid. 55 Myanesin (mephenesin) _.
2 Neutrapen (penicillinase).. 15 Mustargen (nitrogen mustard)_.
58 Nesacaine (chlorprocaine). 53 Murel (valethamate)_..
57 Neraval (methitural) _ 40 Muracil (methylthiouracil).
22 Neptazane (methazolamide) - 36 Mumps virus vaccine- 49 Ncosynephrine (phenylephrine).. 62 Morphine.
Page Page
26. NARCOTIC ANALGESICS
OPIUM DERIVATIVES camphorated tincture of opium (paregoric) pantopon powdered opium powder of ipecac and opium (Dover's powder) tincture of opium (laudanum) Undesirable effects in aviation: Sleepiness from excessive dosage.
Use in aviation personnel: Airman duties contraindicated for 12 hours after use.
MORPHINE DERIVATIVES (AND ANTAGONISTS) apomorphine dihydromorphinone (Dilaudid) heroin levallorphan (Lorfan) levorphanol (Levo-Dromoran) metapon morphine nalorphine (Nalline) oxymorphone (Numorphan) phenazocine (Primadol) Undesirable effects in aviation: Nausea, vomiting, colic, general depression, slowed respiration, vasomotor depression.
Use in aviation personnel: Airman duties contraindicated for 24 hours after use. In most instances the medical condition would preclude work for an additional period.
CODEINE DERIVATIVES codeine dextromethorphan (Romilar) dihydrocodeinone (Codone; Dicodid; Mercodinone) dihydrohydroxycodeinone (contained in Percodan) drocode (Didrate) elixir terpin hydrate and codeine and similar mixtures ethyl morphine (Dionin) pholcodine (Ethnine) 62
Use in avlation personnel: Airman duties not contraindicated in the absence of adverse effects; however, patient should be under close observation for blood changes.
COLCHICINE GROUP colchicine demecolcine (Colcemid) Undesirable effecta in aviation: Purging at upper therapeutic levels.
Use in aviation personnel: Airman duties contraindicated for 48 hours after use.
OTHERS cinchophen (Atophan) neocincophen (Tolysin) phenyramidol (Analexin) Undesirable effects in aviation: The cincophens may produce hepatitis; phenyramidol causes infrequent gastrointestinal distress and pruritis.
Use in avlation personnel: Airman duties not contraindicated in the absence of adverse effects. Medical examinations indicated at 2-week intervals if therapy continuous.
Page Page Pyrazinamide Restrol (dienestrol). 41 Pyribenzamine (tripellenamine). Rhubarb 32 Pyrictal (N-phenylbarbital) - Riboffavin _ 45 Pyridium (phenazopyridine) - Rimifon (isoniazid) Pyridostigmine. Ristocetin 3 Pyridoxine - 45 Ritalin (methylphenidate). 74 Pyrilamine maleate. 37 Robalate (dihydroxyaluminum Pyrimethamine 8 amino acetate) 31 Pyronil (pyrrobutamine) - 37 Robaxin (methocarbamol) - 55 Pyrrobutamine_ 37 Rolicton (amisometradine) 22 Pyrrolazote (pyrathiazlne)_. 37 Rolitetracycline_. 3 Pyruvic acid Isonicotinyl hydra- Romilar (dextromethorphan) . 62 zone_ Roxinold (reserpine). 24, 71 Pyrvinium 13 Rutgers 612 (ethohexadiol) 17 Rythritol (pentaerythritol tetranitrate) 26 Quelicin (succinylcholine) - 55 Quiactin (oxanamide) _. 71 Quide (piperacetazine) - 70 Saff (safflower oil) 23 Quilene (pentapiperide) 53 Safflower oil. 23 Quinacrine. 8, 13 Saffola (safflower oil) - 23 Quinadone (dilodohydroxyquin). 9 Saffolin (safflower oil) - 23 Quinambicide (lodochlorhyd- Salam/de (salicylamide). 60 roxyquin) 9, 17 Salazopyrin (salicylazosulfapy- Quinidine 20 ridine) - 2 Quinine Salicin (salicylamide). 60 Quinine and urea hydrochloride. 59 Salicyl (magnesium trisilicate) 31 Quinine carbacrylio resIn 34 | Salicylamide 60 Quotane (dimethisoquin) 58 Salicylanilide 18 Salicylazosulfapyridine 2 R Salicylic acid 18, 60 Rabies vaccine 36 Saligenin 59 Racephedrine. 49 Salrin (salicylamide) 60 Radloactive chromic chloride. 34 Salvarsan (arsphenamine) - 10 Radioactive vitamin B13- 35 Salyrgan theophylline (mersalyl Radio-iodinated serum albumin. 84 sodium and theophylline) 21 Raudixin (rauwolfia) 71 Sandoptal (allybarbituric acid) - 86 Raulon (rauwolfia) - 71 Sandostene (thenalidine) 37 Rau-Sed (reserpine) - 24, 71 Sandril (reserpine) 71 Rau-Tab (rauwolfia) _ 71 Santonin. 14 Rautensin (rauwolfs) - 71 Sarcolysin. 15 Rauwiloid (alseroxylon) - 71 Saxol (liquid petrolatum) 32 Rauwolfia group - 24 Scarlet fever immune serum 36 Rauwolfia. 71 Scarlet red 18 Ravocaine (propoxycaine) - 68 Scopolamine б4 Regitine (phentolamine).. 51 Scurocaine (procaine) - 58 Relaxin_. 42 Secobarbital 66 Renese (polythiazide) - 22 Seconal (secobarbital) 66 Renstamin (pyrilamine maleate) - 37 Sedormid (allylispropylacetylcar- Rescinamine. 71 bamide) - 66 Reserpine 24, 71 Senna _ 32 Reserpoid (reserpine) - 24, 71 Serfin (reserpine).--. 24, 71 Resorcinol 18 | Bernyl (phencyclidine) - 57 93
Page Pape Serpasil (reserpine) - 24, 71 Spiramycin 3 Serpiloid (reserpine) 24, 71 Spironolactone. 22 Sethyl (homatropine) - Serpine (reserpine) - 71 53 Stanolone Spontin (ristocetin) 42 3 Silver nitrate 18 Stanozolol 42 Silver pierate_ 18 Staphcillin (sodium methicillin) - 2 Silver protein 18 Staphylomycin 3 Silvol (silver protein) - 18 Steclin (tetracycline) - 3 Sinan (mephenesin)- 55 Stelazine (trifluoperazine) - 70 Sinaxar (styramate) 55 Stenediol (methylandrostene- Singoserp (syrosingopine) - 24 diol)_ 42 Sintrom (acenocoumarin) 29 Stibophen 12 Sitosterols. 23 Stigmonene (benzpyrinium). 52, 55 Skin test antigens- 37 Stilbamidine. 12 Skiodan (methioda!) 35 Stilbamine glucoside. 12 Smallpox vaccine. 36 Stilbestrol (diethyletilbestrol) 41 Soap- 19 Stramonium 54 Sodium acetosulfone 4 Streptokinase-streptodornase 29 Sodium bicarbonate. 31, 44 Streptomycin Sodium bromide. 65 Styramate.. 55 Sodium carboxymethyl cellulose- 32 Suavitil (benactyzine) 71 Sodium chloride. 44 Succinylcholine - 55 Sodium dehydrocholate. 32 Succiny lsulfathiazole - 2 Sodium dextrothyroxin 23 Sucostrin (succinylcholine) - 55 Sodium glutamate 47 Sulestrex (piperazine estrone sul- Sodium hypochlorite. 18 fate) - 41 Sodium indigotindisulfonate. 34 Sulfacetamide.
Sodium iodide 41, 64 Sulfadiazine_.
Sodium lactate_. 44 Sulfadimethoxine_ Sodium lauryl sulfate. 19 Sulfaethidole..
Sodium methicillin 2 Sulfa merazine-.
Sodium morrhuate. 19 Sulfa methazine- Sodium p-amminobippurate. 34 Sulfa methizole Sodium perborate 18 Sulfa methoxazole..
Sodium phosphate 32 Sulfa methox ypyridazine Sodium psylliate. 19 Sulfa midine.
Sodium radiochromate 34 Sulfa monomethoxine..
Sodium radio-iodide 35 Sulfamoxole.
Sodlum ricinoleate_ 19 Sulfamyd (aulfacetamide) - Sodium salicylate_ 60 | Sulfaphenazole..
Sodium sulfate_ 32 Su Ifapyridine- Sodium tetradecyl sulfate - 19 Su lfasomizole - - Sodium thiosulfate 34 Su Ifasuxidine (succinylsulfathia- Bolaothyl (corticotropin) - 40 zole)..
Bolganol (aurothioglucose). 10 Sulfathalidine (phthalylsulfathia- Soluthricin (tyrothricin). zole) _.
Soma (carisoprodol) - 55 Sulfazole_. 1 Sombulex (hexobarbital) - 57 Sulfbromphthalein. 34 Sorbitol.. 21 Sulferrous (ferrous sulfate) - 28 Sotradecol (sodium tetracedy) Bulinpyrazone. 23, 60 sulfate). 19 Sulfisomidine_.
Sparine (promazine) -- 70 Sulfsoxazole..
Spartase (potassium and magne- Sulfoxone - sium salts of aspartic aoid) 471 Sulfuno (sulfamoxole)- 94
Page 2 AC 91.11-1 7/19/63
4. AVAILABILITY. Although the contents of the guide should be interpreted and applied by physicians, who know the nature of airman activities, it 18 available to any purchaser. Order it from the Superintendent of Documents, U. S. Government Printing Office, Washington, D. C. 20401.
The purchase price is 55 cents.
1th leighard T, M.D.
Acting Civil Air Surgeon Par 4
file Copy On Shelf Federal spration ne AC NO: AC 91,11-1
SLAVIATON ROS AIR TRAFFIC CONTROL
AND GENERAL OPERATIONS
ADVISORY CIRCULAR ¡EFFECTIVE :
7/19/63
TO STATES OF PARE SUBJECT: GUIDE TO DRUG HAZARDS IN AVIATION
1. PURPOSE. This circular announces the publication and availability of the Guide to Drug Hazards in Aviation Medicine.
2. BACKGROUND. Section 91.11 of the Federal Aviation Regulations states:
91.11 Liquor and drugs.
(a) No person may act as crewmember of a civil aircraft while -
(1) Under the influence of intoxicating liquor; or
(2) A means of determining the type of drug which "affects his faculties" has not, heretofore, been provided to airmen.
The Guide to Drug Hazards in Aviation Medicine consists of a comprehensive list of all commonly-used prescription and nonprescription drugs, suitably indexed. The text of the guide groups those drugs with similar pharmacological effect. For each group a concise statement is made concerning: (1) the side effects, if any, which make them undesirable for use while serving as an airman, and (2) recommendations concerning the length of time an airman should wait after taking a drug before APPLICATION. A copy of the guide is in the possession of all FAA Aviation Medical Examiners.
Examiners are prepared to provide advice and professional interpretation of guide recommendations as they might apply to specific circumstances involving the use of drugs by airmen.